Head to head

Comparisons worth publishing.

Comparisons82

Compounds39

Forty compounds make 780 possible pairings, and almost all of them would be the same page with two names swapped. These are the ones where the data actually differs: same class and same target, or the same primary goal reached two different ways. Every one ends in a written verdict, including the ones where the honest verdict is that there is no winner.

3 comparisons

GLP-1 / incretin

Within-class matchups where both compounds are aimed at the same thing.

Retatrutide vs SemaglutideSemaglutide rests on firmer evidence Retatrutide vs TirzepatideTirzepatide rests on firmer evidence Semaglutide vs TirzepatideRoute decides this one, not potency

21 comparisons

GH secretagogue

Within-class matchups where both compounds are aimed at the same thing.

CJC-1295 with DAC vs CJC-1295 without DACCJC-1295 with DAC rests on firmer evidence CJC-1295 with DAC vs GHRP-2Usually stacked — and GHRP-2 rests on firmer evidence CJC-1295 with DAC vs HexarelinNot an either/or CJC-1295 with DAC vs IpamorelinNot an either/or CJC-1295 with DAC vs MK-677Route decides this one, not potency CJC-1295 with DAC vs SermorelinSermorelin rests on firmer evidence CJC-1295 without DAC vs GHRP-2Usually stacked — and only GHRP-2 has human trial data CJC-1295 without DAC vs HexarelinUsually stacked — and only Hexarelin has human trial data CJC-1295 without DAC vs IpamorelinUsually stacked — and Ipamorelin rests on firmer evidence CJC-1295 without DAC vs MK-677Usually stacked — and only MK-677 has human trial data CJC-1295 without DAC vs SermorelinUsually stacked — and only Sermorelin has human trial data GHRP-2 vs HexarelinNo winner in this data GHRP-2 vs IpamorelinGHRP-2 rests on firmer evidence GHRP-2 vs MK-677Route decides this one, not potency GHRP-2 vs SermorelinNot an either/or Hexarelin vs IpamorelinNo winner in this data Hexarelin vs MK-677Route decides this one, not potency Hexarelin vs SermorelinNot an either/or Ipamorelin vs MK-677Usually stacked; if you must pick, route decides Ipamorelin vs SermorelinUsually stacked — and Sermorelin rests on firmer evidence MK-677 vs SermorelinRoute decides this one, not potency

6 comparisons

Healing & repair

Within-class matchups where both compounds are aimed at the same thing.

ARA-290 vs KPVUsually stacked — and only ARA-290 has human trial data ARA-290 vs LarazotideRoute decides this one, not potency BPC-157 vs KPVNot an either/or BPC-157 vs LarazotideNot an either/or BPC-157 vs TB-500Usually stacked; if you must pick, route decides KPV vs LarazotideUsually stacked — and only Larazotide has human trial data

10 comparisons

Metabolic

Within-class matchups where both compounds are aimed at the same thing.

5-Amino-1MQ vs CagrilintideOne has been tested in people; the other has not 5-Amino-1MQ vs MOTS-cUsually stacked; if you must pick, route decides 5-Amino-1MQ vs SLU-PP-332Not an either/or 5-Amino-1MQ vs TesofensineOne has been tested in people; the other has not Cagrilintide vs MOTS-cNo winner in this data Cagrilintide vs SLU-PP-332One has been tested in people; the other has not Cagrilintide vs TesofensineRoute decides this one, not potency MOTS-c vs SLU-PP-332Usually stacked; if you must pick, route decides MOTS-c vs TesofensineTesofensine rests on firmer evidence SLU-PP-332 vs TesofensineOne has been tested in people; the other has not

11 comparisons

Nootropic

Within-class matchups where both compounds are aimed at the same thing.

Cerebrolysin vs DihexaOne has been tested in people; the other has not Cerebrolysin vs P21Usually stacked — and only Cerebrolysin has human trial data Cerebrolysin vs SelankUsually stacked; if you must pick, route decides Cerebrolysin vs SemaxUsually stacked; if you must pick, route decides Dihexa vs P21Not an either/or Dihexa vs SelankOne has been tested in people; the other has not Dihexa vs SemaxUsually stacked — and only Semax has human trial data DSIP vs SelankUsually stacked — and Selank rests on firmer evidence P21 vs SelankOne has been tested in people; the other has not P21 vs SemaxUsually stacked — and only Semax has human trial data Selank vs SemaxNot an either/or

1 comparison

Immune

Within-class matchups where both compounds are aimed at the same thing.

LL-37 vs Thymosin Alpha-1Usually stacked — and Thymosin Alpha-1 rests on firmer evidence

3 comparisons

Cosmetic

Within-class matchups where both compounds are aimed at the same thing.

GHK-Cu vs Melanotan INo winner in this data GHK-Cu vs Melanotan IINo winner in this data Melanotan I vs Melanotan IINot an either/or

6 comparisons

Other

Within-class matchups where both compounds are aimed at the same thing.

Epitalon vs NAD+Not an either/or Epitalon vs SS-31Not an either/or Kisspeptin-10 vs OxytocinUsually stacked — and Oxytocin rests on firmer evidence Kisspeptin-10 vs PT-141Usually stacked — and PT-141 rests on firmer evidence NAD+ vs SS-31Not an either/or Oxytocin vs PT-141Not an either/or

21 comparisons

Across classes

Different mechanisms that get compared anyway, because they are pointed at the same goal. These are the ones most likely to end in "they do different things".

5-Amino-1MQ vs TesamorelinMetabolicGH secretagogueOne has been tested in people; the other has not Cagrilintide vs MK-677MetabolicGH secretagogueSame score, opposite directions Cagrilintide vs RetatrutideMetabolicGLP-1 / incretinNo winner in this data Cagrilintide vs SemaglutideMetabolicGLP-1 / incretinUsually stacked — and Semaglutide rests on firmer evidence Cagrilintide vs TirzepatideMetabolicGLP-1 / incretinTirzepatide rests on firmer evidence CJC-1295 with DAC vs IGF-1 LR3GH secretagogueOtherNo winner in this data CJC-1295 without DAC vs DSIPGH secretagogueNootropicDSIP rests on firmer evidence CJC-1295 without DAC vs SelankGH secretagogueNootropicOne has been tested in people; the other has not DSIP vs IpamorelinNootropicGH secretagogueNot an either/or DSIP vs SermorelinNootropicGH secretagogueSermorelin rests on firmer evidence Hexarelin vs IGF-1 LR3GH secretagogueOtherOne has been tested in people; the other has not Ipamorelin vs SelankGH secretagogueNootropicSelank rests on firmer evidence MK-677 vs RetatrutideGH secretagogueGLP-1 / incretinSame score, opposite directions MK-677 vs SemaglutideGH secretagogueGLP-1 / incretinSame score, opposite directions MK-677 vs TesofensineGH secretagogueMetabolicSame score, opposite directions MK-677 vs TirzepatideGH secretagogueGLP-1 / incretinSame score, opposite directions Retatrutide vs TesofensineGLP-1 / incretinMetabolicRoute decides this one, not potency Selank vs SermorelinNootropicGH secretagogueRoute decides this one, not potency Semaglutide vs TesofensineGLP-1 / incretinMetabolicNo winner in this data SLU-PP-332 vs TesamorelinMetabolicGH secretagogueOne has been tested in people; the other has not Tesofensine vs TirzepatideMetabolicGLP-1 / incretinRoute decides this one, not potency

Deliberately absent

Compounds with no comparison page

4 compounds have no head-to-head page here, and that is the finding rather than a gap. Their own goal weightings never clear the threshold used to publish a pairing, which is this dataset saying there is no strong enough claim to hold up against anything else. The monographs still cover them.

Educational information only, not medical advice. Talk to a licensed clinician before starting, changing, or stopping anything.