Metabolic

5-Amino-1MQ

Animal data only

A small-molecule nicotinamide N-methyltransferase (NNMT) inhibitor, not a peptide.

OralIntermediateNot approved anywherefat lossmetabolic healthmuscle growthlongevity

Also known as 5-amino-1-methylquinolinium · 5A1MQ · NNMT inhibitor

ANIMAL DATA ONLY

The evidence is animal and cell-culture work. There are no controlled human dosing trials, so every number below is convention rather than a result.

At a glance

Dose summary

Typical dose100 mg
Range50 mg–150 mg
FrequencyDaily
Half-lifeUnknown
ScheduleOnce daily
Cycle length12 weeks
RouteOral
Experience levelIntermediate
Evidence gradeAnimal data only
ApprovalNot approved anywhere
Where the dose comes fromCommunity practice, not a trial

No reliable human half-life has been published for 5-Amino-1MQ, so none is listed rather than guessed at.

No regulator and no trial set these numbers. They describe what people actually do, recorded so you can see the range rather than guess at it — which is not the same thing as a recommendation.

Form

Nothing to reconstitute

5-Amino-1MQ is taken by mouth, not injected, so there is no vial, no diluent and no draw volume. The typical dose is 100 mg per administration — that is the number on the capsule or tablet, and the reconstitution calculator deliberately excludes this compound.

Mechanism & evidence

What it is, and what is known

A small-molecule nicotinamide N-methyltransferase (NNMT) inhibitor, not a peptide. Evidence is preclinical: it reduced fat mass in diet-induced obese mice without changing food intake, and there are cell and rodent data on muscle stem cells. There are no published controlled human trials, so every dose figure here is extrapolated from vendor and community practice rather than clinical data — treat the range as low confidence.

It is taken orally in capsules: 50-150 mg daily, with 100 mg typical, which in the microgram units used throughout this dataset is 50,000-150,000 mcg (100 mg = 100,000 mcg). It is swallowed as capsules rather than reconstituted, so the reconstitution fields do not apply.

Tolerability

Reported side effects

  • Insomnia or restlessness if taken late in the day
  • Mild nausea or stomach upset
  • Headache
  • Jitteriness in sensitive users

Hard stops

Do not use this if

  • Pregnancy, possible pregnancy, or breastfeeding
  • Under 18

These are flags, not a screening. They do not replace a conversation with a clinician who knows your history.

Handling

Storage

Sealed, as supplied24 months
Once opened30 days

Keep it cold, dry and dark. The figures above are shelf-life conventions, not stability testing on the product you bought.

Combinations

Commonly stacked with

Stacking multiplies the side-effect surface and makes it impossible to tell which compound did what. Add one thing at a time.

References

Sources

Educational information only, not medical advice. Talk to a licensed clinician before starting, changing, or stopping anything.