Run for injury repair

Wolverine Stack

beginner8 weeks

The classic two-peptide repair stack: BPC-157 daily for local tendon, ligament and gut healing, plus TB-500 loaded twice weekly for systemic cell migration and tissue remodeling. The most commonly run injury protocol and the base that KLOW was built on top of.

Duration8 wk
Compounds2
Ratio-lockednone
Off standalone range1 of 2

Also sold as Wolverine, BPC-157 + TB-500.

Cautions — 6 on record

Read before running any of this

  1. Neither compound is approved for human use anywhere. Both are research-chemical grade.
  2. Both are pro-angiogenic in animal models, so avoid with an active or recent malignancy.
  3. Not for use in pregnancy.
  4. Both are banned by WADA. Do not run this if you are drug tested in sport.
  5. Pain relief can outrun actual structural healing. The commonest way this stack causes harm is people returning to full load too early because the joint stopped hurting.
  6. Run a defined block and then stop. Continuous year-round use has no supporting data.

Components

What is in it, and when

CompoundDoseFrequencyTimeNotes
BPC-157500 mcg200 mcg500 mcgOnce daily7×/weekAny timeOften split into two 250 mcg shots morning and evening. For a specific injury people inject subcutaneously as near the site as is safe; for gut work the oral route is used instead.Calculator →
TB-5002.5 mg2 mg2.5 mgTwice a week2×/weekAny timeLoading dose for the first 4-6 weeks, then most people drop to 2-2.5 mg once weekly for maintenance. TB-500 is systemic - injecting it near the injury buys nothing.Calculator →

Doses are per administration, in the canonical unit. The second line under each dose is the range people run. Each calculator link prefills the reconstitution math for that component.

Delivered dose vs standalone dose

How these doses compare to running each compound alone

Each bar is that compound’s own dose range from its monograph, with a marker where this protocol puts it. A marker outside the band means the protocol is not dosing that compound the way it is dosed on its own — for a fixed-ratio vial that is arithmetic, not a choice.

BPC-157

At the ceiling of the range
Standalone 200 mcg500 mcg (typical 250 mcg)This protocol 500 mcg
Per dose
200% of typical
Per week
3.5 mg · 200% of standalone
Cycle total
28 mg · 56 doses

Often split into two 250 mcg shots morning and evening. For a specific injury people inject subcutaneously as near the site as is safe; for gut work the oral route is used instead.

TB-500

Above standalone range
Standalone 200 mcg500 mcg (typical 300 mcg)This protocol 2.5 mg
Per dose
833% of typical
Per week
5 mg · 238% of standalone
Cycle total
40 mg · 16 doses

Dosed twice a week here against once daily standalone, so the weekly figure is the fairer of the two comparisons.

Loading dose for the first 4-6 weeks, then most people drop to 2-2.5 mg once weekly for maintenance. TB-500 is systemic - injecting it near the injury buys nothing.

Schedule — 8 weeks

Week by week

Dosing weeks for each component of Wolverine Stack
Compound1Week 1Week 2Week 34Week 4Week 5Week 6Week 78Week 8Cycle total
BPC-157500 mcg · 7×/wk
28 mg56 doses
TB-5002.5 mg · 2×/wk
40 mg16 doses
dosing past that compound’s own typical cycle length

This protocol outlasts some of its own components

  • TB-500 is typically cycled for 6 weeks; this protocol runs 8 weeks, so weeks 78 are past that. In a fixed-ratio vial you cannot drop it early without dropping everything else with it.

The dataset records one dose per component, so every dosing week is identical. Where a protocol note describes a loading phase followed by maintenance, that phase change is in the note, not in the schedule — read the component notes before assuming the grid is the whole story.

Evidence

What is actually known

Strong animal data for both on tendon, ligament, muscle and gut healing; essentially no controlled human trial data for either, and none at all for the combination. Doses come from long-standing community practice, not from a label.

SourcesPubMed

Educational information only, not medical advice. Talk to a licensed clinician before starting, changing, or stopping anything.